LEGAL DISCLAIMER

Welcome to the Cardioviva™ website. The information provided on this site is for general informational and educational purposes only. Read and review these Terms of Use carefully before accessing or using this web site. By accessing or using this site, you acknowledge that you have read, understood and agreed to the Terms of Use Agreement. If you do not agree to the Terms of Use, you may not access or use the site.


Information in these materials is not intended to replace and should not be used as a substitute for the medical care and advice of a physician or other qualified healthcare professional.


The information provided in this animation is an introduction to Cardioviva™ and probiotics and does not purport to be a complete discussion of nutrition, probiotics, or physical health or any component thereof. The information should not be construed as a claim or representation that any procedure or product mentioned constitutes cure, palliative or remedy for any condition. The information in these materials has not been reviewed, evaluated, or approved by the Food and Drug Administration, Health Canada, or any other regulatory agency and is not approved to diagnose, treat, cure, or prevent disease. You should not use the information in these materials for pursuing any particular treatment plan, diagnosing or treating a health problem or disease, or prescribing any medication or other treatment. Each individual is different, the effects of consuming the products described in these materials may vary from person to person. Although clinical studies have suggested correlations between Cardioviva™ and certain health benefits, no claims or guarantees can be made as to the effects of Cardioviva™ or related probiotic products on any particular individual's health and well-being.


Use of the website

The information provided on this site is for general informational and educational purposes. Certain sections of this web site are intended for particular audiences including Micropharma Limited employees, customers and shareholders, as well as members of the health care community and the general public. Your access to and use of the information contained in the web site is subject to this Terms of Use Agreement. By accessing and using this web site, you accept, without limitation or qualification, this Terms of Use Agreement.


Copyrights

The entire contents of this web site are subject to copyright protection. Copyright © 2003-2012 Micropharma Limited. All rights reserved. The contents of this web site may not be copied other than for non-commercial individual reference with all copyright or other proprietary notices retained, and thereafter may not be recopied, reproduced or otherwise redistributed. Except as expressly provided above, you may not otherwise copy, display, download, distribute, modify, reproduce, republish or retransmit any information, text or documents contained in this web site or any portion thereof in any electronic medium or in hard copy, or create any derivative work based on such images, text or documents, without the express written consent of Micropharma Limited. Nothing contained herein shall be construed as conferring by implication, estoppel or otherwise any license or right under any patent or trademark of Micropharma Limited, or any third party.


Void Where Prohibited. This web site and its contents are intended to comply with the laws and regulations in Canada. Although the information on this web site is accessible to users outside of Canada, the information on the web site pertaining to Micropharma Limited products is intended for use only by residents of Canada. Other countries may have laws, regulatory requirements and medical practices that differ from those in Canada. This site links to other sites produced by Micropharma Limited various operating divisions and subsidiaries, some of which are outside Canada. Those sites may have information that is appropriate only to that particular originating country. Micropharma Limited reserves the right to limit provision of our products or services to any person, geographic region or jurisdiction and/or to limit the quantities or any products or services we provide. Any offer for any product or service made on this web site is void where prohibited.


Trademarks

All product names, whether or not appearing in large print or with the trademark symbol, are trademarks of Micropharma Limited, its affiliates, related companies or its licensors or joint venture partners, unless otherwise noted. The use or misuse of these trademarks or any other materials, except as permitted herein, is expressly prohibited and may be in violation of copyright law, trademark law, the law of slander and libel, the law of privacy and publicity, and communications regulations and statutes. Please be advised that Micropharma Limited actively and aggressively enforces its intellectual property rights to the fullest extent of the law.


Use of the website

The information provided on this site is for general informational and educational purposes. Certain sections of this web site are intended for particular audiences including Micropharma Limited employees, customers and shareholders, as well as members of the health care community and the general public. Your access to and use of the information contained in the web site is subject to this Terms of Use Agreement. By accessing and using this web site, you accept, without limitation or qualification, this Terms of Use Agreement.


Non-confidential information

Subject to any applicable terms and conditions set forth in our Privacy Policy, any communication or other material that you send to us through the internet, or post on the web site by electronic mail or otherwise, such as any questions, comments, suggestions or the like, is and will be deemed to be non-confidential and Micropharma Limited shall have no obligation of any kind with respect to such information. Micropharma Limited shall be free to use any ideas, concepts, know-how or techniques contained in such communication for any purpose whatsoever, including but not limited to, developing, manufacturing and marketing products.


Indemnification

You agree to indemnify, defend and hold harmless Micropharma Limited, its officers, directors, employees, agents, suppliers and third party partners from and against all losses, expenses, damages and costs, including reasonable attorneys' fee, resulting from any violation by you of these Terms of Use.


Privacy. Micropharma Limited respects the privacy of its web site users. Please refer to Micropharma Limited Privacy Policy that explains users' rights and responsibilities with respect to information that is disclosed on this web site.


Miscellaneous

If any provision of this Agreement is held to be unlawful, void or unenforceable, then such provision shall be severable without affecting the enforceability of all remaining provisions. Micropharma Limited reserves the right to alter or delete materials from this web site at any time at its discretion.


Third party web sites and links

This web site may contain links or references to other web sites maintained by third parties over whom Micropharma Limited has no control. Such links are provided merely as a convenience. Similarly, this web site may be accessed from third party links over whom Micropharma Limited has no control. Micropharma Limited makes no warranties or representations of any kind as to the accuracy, currency, or completeness of any information contained in such web sites and shall have no liability for any damages or injuries of any kind arising from such content or information. Inclusion of any third party link does not imply an endorsement or recommendation by Micropharma Limited.


Content

Micropharma Limited will use reasonable efforts to include accurate and up-to-date information on this web site but Micropharma Limited makes no warranties or representations of any kind as to its accuracy, currency or completeness. You agree that access to and use of this web site and the content thereof is at your own risk. Micropharma Limited disclaims all warranties, express or implied, including warranties of merchantability of fitness for a particular purpose. Neither Micropharma Limited nor any party involved in creating, producing or delivering this web site shall be liable for any damages, including without limitation, direct, incidental, consequential, indirect or punitive damages, arising out of access to, use of or inability to use this web site, or any errors or omissions in the content thereof. This limitation includes damages to, or for any viruses that infect, your computer equipment.


Governing Laws

This Terms of Use Agreement and your use of the web site shall be governed by the laws of Canada and the Province of Ontario without regard to its conflicts of laws principles. Any legal action or proceeding related to this web site shall be brought exclusively in a federal or provincial court of competent jurisdiction sitting in Ontario.



PRIVACY POLICY

This Privacy Notice applies to information, including personal information, collected about you by Cardioviva™.


Information we collect

We collect information about you from a variety of sources, including:

- Information we collect from you directly.

- Information we collect about you when you visit our site, use our services, or view our online advertisements.

- Information we collect about you from other sources, such as commercially available sources.


We collect information about you from a variety of sources, including: Information we collect from you directly. Information we collect about you when you visit our site, use our services, or view our online advertisements. Information we collect about you from other sources, such as commercially available sources. All the information we collect about you may be combined to help us tailor our communications to you and to develop world-class products and services.


Your Choices

We give you choices about how we communicate with you. You can stop receiving promotional email or postal communications from a particular Micropharma brand or program through this Privacy Notice. Please inquire and learn how to complete your request.


Uses/information sharing

We use the information we collect to provide the products and services you request, to tell you about other products and services offered by Micropharma, and to manage our sites and services. In general, we do not share your personal information with third-party marketers, unless we have asked for and obtained your explicit consent. We may share your information: With our third-party service suppliers, including those who work on behalf of Micropharma and our business partners to send you joint communications that we hope you find of interest. If a Micropharma brand is sold to another company. To protect and defend the right and property of Micropharma (including enforcing our Terms and Conditions). When required by law, and / or public authorities.


REFERENCES

Jones ML, Martoni CJ, Parent M, Prakash S. Cholesterol-lowering efficacy of a microencapsulated bile salt hydrolase-active Lactobacillus reuteri NCIMB 30242 yoghurt for­mulation in hypercholesterolaemic adults. Br J Nutr. 2012 May; 107 (10):1505-13. Epub 2011 Nov 92


Jones ML, Martoni CJ, Prakash S. Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial. 2012b; Accepted by Eur J Clin Nutr.


Jones ML, Martoni CJ, Tamber S, Parent M, Prakash S. Evaluation of safety and tolerance of microencap­sulated Lactobacillus reuteri NCIMB 30242 in a yogurt formulation: A randomized, placebo-controlled, double-blind study. Food Chem Toxicol 2012; 50(6):2216-2223.


Jones ML, Martoni CJ, Di Pietro E, Simon RR, Prakash S. Evalua­tion of clinical safety and tolerance of a Lactobacillus reuteri NCIMB 30242 supplement capsule: a rando-mized control trial. Regul Toxicol Pharmacol. 2012; 63(2):313-320.


Branton WB, Jones ML, Tomaro- Duchesneau, Martoni C, Prakash S. In vitro characterization and safety of the probiotic strain Lactobacillus reuteri cardioviva NCIMB 30242. Int J of Probiotics and Prebiotics. 2010 6(1):1-12.


Demonty I, Ras RT, van der Knapp HCM, Duchateau GSMJE, Meijer L, Zock P, Geleijnse J, Trautwein E. Continuous Dose-Response Re­lationship of the LDL-Cholester­ol?Lowering Effect of Phytosterol Intake. J Nutr. 2009;139(2):271-84.


Alsheikh A, Asli G, Weizman Z. Effect of a probiotic formula on in­fections in child care centers: comp-arison of two probiotic agents. Pedi­atrics 2005; 115(1):5-9.


Alsheikh A, Weizman Z. Safety and tolerance of a probiotic formula in early infancy comparing two probi­otic agents: a pilot study. J Am Col Nutr.2006; 25(5):415-419.


Health Canada. PLA Exemption Number (EN-160554): http://web­prod3.hc-sc.gc.ca/product-produit/productsReq.do?srchEnTxt=16055 4&srchCoTxt=&srchBrMqTxt=& mthd=Search&lang=eng. Accessed Aug. 31, 2012.


U.S. Food and Drug Administra­tion. GRAS Notice Inventory, Oct. 18, 2011 date of filing, under review. GRN No. 409: http://www.accessda­ta.fda.gov/scripts/fcn/fcnDetailNavi­gation.cfm?rpt=grasListing&id=409. Accessed Aug. 31, 2012.


European Food Safety Authority. Sci­entific Opinion of the Panel on Bio­logical Hazards. The maintenance of the list of QPS microorganisms intentionally added to food or feed. (Question No EFSA-Q-2008-006) Adopted on 10 Dec. 2008.The EFSA Journal 2008; 923: 1-48.


The Economist. The human micro­biome: Me, myself, us. http://www. economist.com/node/21560523 Accessed Aug. 31, 2012.


Abumweis et al., 2008; Ortega et al., 2006; Talati et al., 2010; FDA, 2010; EFSA 2012


Hooper et al. 2004; Skulas-Ray et al., 2011; EFSA, 2012;


Othman et al. 2011; Tiwari and Cummins, 2011; EFSA, 2010; EFSA, 2011; NCEP-ATP III, 2002III, 2002


Wei et al., 2009; Anderson et al., 2000; NCEP-ATP III, 2002


McVeigh et al., 2006; Anderson and Bush, 2011; FDA, 1999; Erdman, 2000; NCEP-ATP III, 2002